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Stone Root - Some Benefits on Usage of Stone Root

Taxonomic Class

Lamiaceae

Common Trade Names

Tincture Collinson

Common Forms

Available as tincture of the root.

Source

Stone root is derived from the rhizome and root of Collinsonia canadensis. The plant is native to North America, growing wild from Massachusetts and Vermont west to Wisconsin and south to Florida and Arkansas.

Chemical Components

The rhizome and roots of the C. canadensis contain saponins, tannins, mucilage, and resins.

Actions

The active chemical compounds of the plant show antifungal, astringent, and diuretic properties. Antifungal activity has been demonstrated in vitro using an alcoholic extract of the powdered roots. Tannins produce the characteristic astringent effect. The active ingredient responsible for the diuretic action is unknown. In the treatment of burns, the proteins of exposed tissue are precipitated. An antiseptic, protective coat forms and allows for regeneration of new tissue underneath .

Reported Uses

Stone root is used as a diuretic in several OTC preparations that claim to treat edema, hypertension, and menstrual distress. The herb has also been reported as useful in treating headaches and indigestion.

Its main use is claimed to be for the treatment of diarrhea, hemorrhoids, and varicose veins. These claims are based on the herb's astringent properties. There is no scientific evidence for any of these therapeutic claims.

Recommended Dosage for Best Results

For diuretic action and for treating bladder stones, 15 to 60 gtt of the tincture P.O. t.i.d.

Adverse Reactions

CV: increased blood pressure (with long-term use).

Interactions

Antihypertensives: May have an additive hypotensive effect. Monitor the patient's blood pressure.

Contraindications and Precautions

Stone root is contraindicated in pregnant or breast-feeding patients; effects are unknown. Use cautiously in patients with hypertension.

Special Considerations for Ston Root

Monitor liver function test results; prolonged use of stone root may lead to hepatotoxicity.

Urge the patient to seek appropriate medical advice before self­medicating for high blood pressure or edema.

Instruct the patient to notify the prescriber and pharmacist of any herbal or dietary supplement he is taking when filling a new prescription.

Points of Interest

An FDA advisory review panel on menstrual drug products found little scientific evidence to support the use of stone root.

Commentary

The major therapeutic claims for the use of stone root include its astringent and diuretic activities. None of the therapeutic claims has been substantiated in the scientific literature in either animal or human models; therefore, this herb cannot be recommended.

   

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